Hedgehog signaling activation in human cancer and its clinical implications
(Sprache: Englisch)
Understanding the role of hedgehog signaling in cancer is critically important for novel cancer therapeutics in humans. This volume provides insightful views suitable for clinical scientists, and graduate and undergraduate students alike.
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Understanding the role of hedgehog signaling in cancer is critically important for novel cancer therapeutics in humans. This volume provides insightful views suitable for clinical scientists, and graduate and undergraduate students alike.
Inhaltsverzeichnis zu „Hedgehog signaling activation in human cancer and its clinical implications “
Chapter 1- Overview of hedgehog signaling pathwayChi-chung Hui and Jin Jiang
Chapter 2- Regulation of Hh morphogene gradient
G. D'Angelo, F. Wendler, K. Ayers and P.P. Thérond
Chapter 3- Smoothened Signaling through a G-protein Effector Network
David J. Robbins and Stacey K. Ogden
Chapter 4- Kinases and phosphatases in hedgehog signaling
Jianhang Jia
Chapter 5- Signaling Cross-talk of Oncogenic KRAS and Hedgehog Pathways in Pancreatic Cancer
Xiaodong Cheng
Chapter 6- Crosstalks between PKC and hedgehog signaling
Jing Li and Mark Evers
Chapter 7- Activation of Hh signaling in human cancer
Jingwu Xie and Ervin Epstein
Chapter 8- Hedgehog signaling in pediatric brain tumors
Joon Won Yoon, Ph.D., Jason Fangusaro, M.D., Philip Iannaccone, M.D., Ph.D., and David Walterhouse, M.D.
Chapter 9- Hedgehog Signaling in Mammary Gland Development and Breast Cancer
Adriana P. Visbal and Michael T. Lewis
Chapter 10- Hedgehog signaling and cancer therapeutic resistance
K.S. Clifford Chao and Yu-Jen Chen
Chapter 11- Small-molecule Inhibitors of the Hedgehog Pathway
Ari J. Firestone and James K. Chen
Chapter 12- Cyclopamine and its derivatives for cancer therapeutics
Martin Tremblay and Karen McGovern
Bibliographische Angaben
- 2014, 2011, IX, 217 Seiten, Maße: 15,5 x 23,5 cm, Kartoniert (TB), Englisch
- Herausgegeben: Jingwu Xie
- Verlag: Springer, Berlin
- ISBN-10: 1489995412
- ISBN-13: 9781489995414
Sprache:
Englisch
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