Superantigens

Animal Models Used to Study Superantigen-Mediated Diseases.- Identification, Purification, and Characterization of Staphylococcal Superantigens.- Strain Discrimination of Staphylococcus Aureus Using Superantigen Profiles.- Crystallization and Structure Determination of Superantigens and Immune Receptor Complexes.- Lipopolysaccharide-Induced Toxic Shock Syndrome in Rabbits.- Aortic Valve Damage for the Study of Left-Sided, Native Valve Infective Endocarditis in Rabbits.- Rabbit Model for Superantigen-Mediated Lethal Pulmonary Disease.- Nasopharyngeal Infection of Mice with Streptococcus Pyogenes and In Vivo Detection of Superantigen Activity.- Mini-Osmotic Pump Infusion Model to Investigate the Systemic Effects of Chronic Continuous Exposure to Staphylococcal Superantigen in Mice.- A Sub-Lethal Swine Model for Defining In Vivo Superantigen-Induced Responses Following Exposure to Staphylococcal Enterotoxin B.- Monkey Feeding Assay for Testing Emetic Activity of Staphylococcal Enterotoxin.- Use of an Ex-Vivo Porcine Mucosal Model to Study Superantigen Penetration.- Protocol for Examining Human Vaginal Epithelial Cell Signaling in Response to Staphylococcal Superantigens.- Organ Culture as a Model System for Studies on Enterotoxin Interactions with the Intestinal Epithelium.- Quantification of a Selective Expansion of T Cell Receptor Vbeta by Superantigen Using Real Time PCR.- Induction of Human Regulatory T Cells with Bacterial Superantigens.- Construction of Recombinant Single Chain Variable Fragment (ScFv) Antibody Against Superantigen for Immunodetection Using Antibody Phage Display Technology.