Surface Enhanced Raman Spectroscopy for Biophysical Applications
Using Plasmonic Nanoparticle Assemblies
(Sprache: Englisch)
The book explores the phenomenon of surface-enhanced Raman scattering (SERS), the huge amplification of Raman signal from molecules in the proximity of a metallic nanostructured surface, allowing readers to gain an in-depth understanding of the...
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Klappentext zu „Surface Enhanced Raman Spectroscopy for Biophysical Applications “
The book explores the phenomenon of surface-enhanced Raman scattering (SERS), the huge amplification of Raman signal from molecules in the proximity of a metallic nanostructured surface, allowing readers to gain an in-depth understanding of the mechanisms affecting the spectroscopic response of SERS-active systems for effective applications. SERS spectroscopy is an ultrasensitive analytical technique with great potential for applications in the field of biophysics and nanomedicine. As examples, the author presents the design of nanocolloid-based SERS-active substrates for molecular sensing and of a folate-based SERS-active nanosensor capable of selectively interacting with cancer cells, enabling cancer diagnostics and therapy at the single-cell level. The author also suggests novel paths for the systematization of the SERS nanosystem design and experimental protocols to maximize sensitivity and reproducibility, which is essential when real-world biomedical applications arethe goal of the study. With a combined approach, both fundamental and applied, and a detailed analysis of the state of the art, this book provides a valuable overview both for students new to SERS spectroscopy and for experts in the field.
Inhaltsverzeichnis zu „Surface Enhanced Raman Spectroscopy for Biophysical Applications “
Introduction.- Traditional Raman and SERS: fundamentals and state of the art.- Investigation on nanoparticles and their molecular functionalization.- Nanoparticle-based SERS substrates for molecular sensing applications.- SERS-active nanovectors for single-cell cancer screening and theranostics.- Conclusions.
Autoren-Porträt von Claudia Fasolato
Claudia Fasolato received her Master Degree in Condensed Matter Physics in October 2013. She started her Ph.D. in Sapienza University in November 2013 working on plasmonic nanoparticle assemblies for Surface Enhanced Raman Spectroscopy under the supervision of Prof. P. Postorino. In February 2017, she was awarded her Ph.D. in Physics summa cum laude. Since April 2017, she has worked as a postdoc in the Nanophononics Group of Prof. I. Zardo at the University of Basel.
Bibliographische Angaben
- Autor: Claudia Fasolato
- 2018, 1st ed. 2018, XVIII, 155 Seiten, 59 farbige Abbildungen, Maße: 16 x 24,1 cm, Gebunden, Englisch
- Verlag: Springer, Berlin
- ISBN-10: 3030035557
- ISBN-13: 9783030035556
- Erscheinungsdatum: 17.12.2018
Sprache:
Englisch
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