Therapeutic Antibodies

Historical Development of Monoclonal Antibody Therapeutics.- Preclinical Safety Evaluation of Monoclonal Antibodies.- Molecular Developments in Antibody Production.- Engineering Antibodies for Stability and Efficient Folding.- Human Monoclonal Antibodies from Transgenic Mice.- Antibodies to Cytokines.- Anti-TNF Antibodies: Lessons from the Past, Roadmap for the Future.- Therapeutic Anti-VEGF Antibodies.- Humanized Antihuman IL-6 Receptor Antibody, Tocilizumab.- Antibodies to Cell Markers.- Anti-CD20Monoclonal Antibody in Rheumatoid Arthritis and Systemic Lupus Erythematosus.- Herceptin.- The Use of CD3-Specific Antibodies in Autoimmune Diabetes: A Step Toward the Induction of Immune Tolerance in the Clinic.- Monoclonal Antibody Therapy for Prostate Cancer.- Anti-IgE and Other Antibody Targets in Asthma.- Development of Antibody-Based Cellular and Molecular Therapies.- Cytokine, Chemokine, and Co-Stimulatory Fusion Proteins for the Immunotherapy of Solid Tumors.- The T-Body Approach: Redirecting T Cells with Antibody Specificity.- Intracellular Antibodies (Intrabodies) and Their Therapeutic Potential.